2 List three host reactions when a biomaterial is implanted

2. List three host reactions when a biomaterial is implanted in the body. What are the common problems with the replacement heart valves and hip replacements?

Solution

Host reaction includes-1.injury,2.blood material interaction,

3.provisional matrix formation,4.acute inflammtion,5.chrinic inflammation,6.granulation tissue ,7.foreign body sensation ,8.fibrosis.9.capsule developement.

Common problem with heart valve replacement-

1.bleeding during or after treatment or damage to blood vessel.

2 blood clots that can cause heart attcak , stroke , or lung problem

3 infection at incision site

4.infection in new valve (endocarditis) whixh is more common with heary replacement

5.pneumonia

6.breathin problem

7.arrythmia

8.vlave failure

9. Bad reaction to anasthesia

Common problem with hip replacement-

1.blood clot within leg called deep vein thrombosis

2 osteoarthritis

3.pain ,hip discomfort interfere with patient ability to walk

4.hip joint loosening or dislocation

5.componant loosening and hypersensitivity

6change in leg length

7 fracture.


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