how have integrins previously been considered purely structu

how have integrins previously been considered purely structural? what are the functions of integrins?

Solution

Integrins are the principal receptors used by animal cells to bind to extracellular matrix. They are heterodimers and function as transmembrane linkers between the extracellular matrix and the actin cytoskeleton. A cell can regulate the adhesive activity of its integrins from within.

An integrin molecule is composed of two non covalently associated transmembrane glycoproteins alpha and beta which are considered to be purely structural in nature.