A high fever causes an enzyme to lose its three dimensional

A high fever causes an enzyme to lose its three dimensional structure and function. polar covalent bonds ionic bonds non-polar covalent bonds hydrogen bonds

Solution

A high fever causes an enzyme to lose its three dimensional structure and function. The three dimensional structures of proteins are maintainined by non covalent interactions. Ionic interactions is a type of non covalent bond involved in maintaining three dimensional structure of proteins. Therefore, the answer for this question is option 2 (ionic bonds).